Topical thyroid regrows skin tissue and increases thickness

[BrahminBoss]

Abstract
The present study concerns the effect of topical treatment with a cream formulation of triiodothyroacetic acid (TRIAC) in comparison with a placebo preparation in producing a reversal of skin atrophy induced by long-term employment of topical glucocorticoid therapy in humans. A total of 39 patients with clinically verified skin atrophy due to long-term use of topical potent glucocorticoids were randomized. The changes in skin thickness, elastic fibers, and hyaluronic acid were evaluated by means of sonography and histology. After 8 weeks' treatment, the skin thickness measured by sonography increased by 16% in the epidermis, 8% in the dermis, and epidermis + dermis in the placebo group. In the TRIAC 0.1% group, the corresponding values were 24% ( p=0.063) in the epidermis, 28% ( p=0.042) in the dermis, and 25% ( p=0.039) in the epidermis + dermis. After 8 weeks, in the placebo group, the skin thickness measured by biopsy increased by 5% in the epidermis, epidermis + dermis, and 6% in the dermis. In the TRIAC 0.1% group, the corresponding values were 31% ( p=0.041) in the epidermis, 46% ( p=0.041) in the dermis and 44% ( p=0.043) in the epidermis + dermis. After 8 weeks, the elastic fibers of moderately irregular and thickened fibers increased by 56% in the placebo group and 100% ( p=0.043) in the TRIAC 0.1 group. This study indicates that topical treatment with TRIAC appears to reverse glucocorticoid-induced skin atrophy under the narrow conditions tested.

@TsarTsar444 @PseudoMaxxer @Napoleon1800

 

[wsada]

Good thread

 

[Napoleon1800]

Abstract
The present study concerns the effect of topical treatment with a cream formulation of triiodothyroacetic acid (TRIAC) in comparison with a placebo preparation in producing a reversal of skin atrophy induced by long-term employment of topical glucocorticoid therapy in humans. A total of 39 patients with clinically verified skin atrophy due to long-term use of topical potent glucocorticoids were randomized. The changes in skin thickness, elastic fibers, and hyaluronic acid were evaluated by means of sonography and histology. After 8 weeks' treatment, the skin thickness measured by sonography increased by 16% in the epidermis, 8% in the dermis, and epidermis + dermis in the placebo group. In the TRIAC 0.1% group, the corresponding values were 24% ( p=0.063) in the epidermis, 28% ( p=0.042) in the dermis, and 25% ( p=0.039) in the epidermis + dermis. After 8 weeks, in the placebo group, the skin thickness measured by biopsy increased by 5% in the epidermis, epidermis + dermis, and 6% in the dermis. In the TRIAC 0.1% group, the corresponding values were 31% ( p=0.041) in the epidermis, 46% ( p=0.041) in the dermis and 44% ( p=0.043) in the epidermis + dermis. After 8 weeks, the elastic fibers of moderately irregular and thickened fibers increased by 56% in the placebo group and 100% ( p=0.043) in the TRIAC 0.1 group. This study indicates that topical treatment with TRIAC appears to reverse glucocorticoid-induced skin atrophy under the narrow conditions tested.

@TsarTsar444 @PseudoMaxxer @Napoleon1800

Link to original article?

 

[BrahminBoss]

Link to original article?

Action of topical thyroid hormone analogue, triiodothyroacetic acid in reversing glucocorticoid-induced skin atrophy in humans - PubMed

The present study concerns the effect of topical treatment with a cream formulation of triiodothyroacetic acid (TRIAC) in comparison with a placebo preparation in producing a reversal of skin atrophy induced by long-term employment of topical glucocorticoid therapy in humans. A total of 39...

www.ncbi.nlm.nih.gov

 

[SensitiveYoungMan]

Did you try this?

 

[BrahminBoss]

Did you try this?

Hard to get a carrier , dmso on facial skin I’ve heard reports of it being irritating . I wish they market topical t3

 

[SensitiveYoungMan]

Hard to get a carrier , dmso on facial skin I’ve heard reports of it being irritating . I wish they market topical t3

Yeah, i've had the same problem.

 

[BrahminBoss]

Yeah, i've had the same problem.

U tried dmso?

 

[SensitiveYoungMan]

U tried dmso?

Nah, i've tried many solutions, i think anything that isn't hyaluronic acid or an oil carrier will probably do more harm than not, it will dry the skin out.

 

[BrahminBoss]

Nah, i've tried many solutions, i think anything that isn't hyaluronic acid or an oil carrier will probably do more harm than not, it will dry the skin out.

Did u read the article that said t3 ceases fat burning after a while because BAT resistance? And administering a special adipose tissue targeter tripled weight loss. Fk broo they gatekeepe everything

 

[SensitiveYoungMan]

Did u read the article that said t3 ceases fat burning after a while because BAT resistance? And administering a special adipose tissue targeter tripled weight loss. Fk broo they gatekeepe everything

No, I didn't. The only time I got rapid weight loss from t3 was when I was taking a quarter cynomel 6x a day.

 

[SensitiveYoungMan]

Did u read the article that said t3 ceases fat burning after a while because BAT resistance? And administering a special adipose tissue targeter tripled weight loss. Fk broo they gatekeepe everything

do you have the link?

 

[BrahminBoss]

do you have the link?

Adipose-targeted triiodothyronine therapy counteracts obesity-related metabolic complications and atherosclerosis with negligible side effects - PubMed

Thyroid hormone (TH) is a thermogenic activator with anti-obesity potential. However, systemic TH administration has no obvious clinical benefits on weight reduction. Herein we selectively delivered triiodothyronine (T3) to adipose tissues by encapsulating T3 in liposomes modified with an...

pubmed.ncbi.nlm.nih.gov